AN UNBIASED VIEW OF PALMITOYLETHANOLAMIDE

Of note is usually that, because of PEA’s large lipophilicity, micronized or ultra-micronized formulations are believed to get extra conveniently absorbable, with additional favorable pharmacokinetics and increased efficacy. Though There is certainly some proof supporting this concept, there remains no proof with the superiority of micronized PEA

PEA guards versus bacterial an infection via innate immune modulation involving MCs, macrophages and microglia. Prophylactic PEA in a dose of 0.one mg/kg physique excess weight prolonged survival fee and decreased neuro-inflammation in an aged murine bacterial meningitis design, inside the absence of antibiotics [forty two].Palmitoylethanolamide (P